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NFL Week 4 Predictions: Chiefs Face Ravens Test, Packers Battle Cowboys in High-Stakes Clashes

By: Ratan Datta

On: Sunday, September 28, 2025 7:06 AM

NFL Week 4 Predictions Chiefs Face Ravens Test, Packers Battle Cowboys in High-Stakes Clashes
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The NFL enters Week 4 with a slate of matchups that could reshape early playoff narratives. Following last week’s dramatic finishes — including the Cleveland Browns’ upset over the Green Bay Packers and the Philadelphia Eagles’ walk-off field goal block against the Los Angeles Rams — the action continues with pivotal games across the league.

CBS Sports and SportsLine analysts have broken down every fixture, offering betting odds, spread predictions, and expert insights. Here’s a look at some of the most intriguing contests this week.

Vikings vs Steelers in Dublin

Sunday, 9:30 a.m. ET on NFL Network | Venue: Dublin, Ireland

Minnesota (2-1) enters as slight favorites (-2.5), but experts believe the Pittsburgh Steelers’ aggressive pass rush could prove decisive. “Carson Wentz won’t have the luxury of playing with a big cushion this week. The Steelers’ defense will pressure him throughout,” noted CBS Sports writer John Breech.

Commanders at Falcons

Sunday, 1 p.m. ET on CBS

The Washington Commanders (2-1) are favored by two points over the Atlanta Falcons (1-2). SportsLine’s projection model, which simulates every game 10,000 times, predicts a 29-20 Washington victory, despite quarterback Jayden Daniels’ ongoing knee concerns.

Saints at Bills

Sunday, 1 p.m. ET on CBS

The Buffalo Bills (3-0) are heavy 15.5-point favorites against the winless New Orleans Saints (0-3). Analyst R.J. White suggests Buffalo is among the safest survivor pool picks, though alternative strategies may be necessary if players have already used the Bills earlier in the season.

Also read: Lego Nintendo Game Boy Set Is Here — A Must-Have Collectible for Retro Gaming Fans

Browns at Lions

Sunday, 1 p.m. ET on Fox

After stunning Green Bay last week, the Cleveland Browns face a daunting task in Detroit. The Lions (2-1) are projected to cover a double-digit spread, with SportsLine simulations backing them as part of a longshot parlay returning significant value.

Ravens at Chiefs – Game of the Week

Sunday, 4:25 p.m. ET on CBS

Kansas City and Baltimore both enter with 1-2 records, making this clash critical. While Patrick Mahomes has historically dominated Lamar Jackson (5-1 career record), CBS analysts favor the Ravens at -2.5. “Baltimore has been more balanced despite turnovers, while the Chiefs’ offense has hit historic lows under Mahomes,” explained writer Tyler Sullivan.

Packers at Cowboys – Prime-Time Showdown

Sunday, 8:20 p.m. ET on NBC

Green Bay (2-1) visits Dallas (1-2) in one of the NFC’s most anticipated clashes. The Cowboys’ defense, led by Micah Parsons, will look to contain Jordan Love and the Packers’ offense. SportsLine expert R.J. White, who boasts a strong track record in Packers-related picks, leans toward a low-scoring affair, suggesting the Under may be the safer play.

Jets vs Dolphins – Searching for First Win

Monday, 7:15 p.m. ET on ESPN

Both the New York Jets and Miami Dolphins remain winless at 0-3. Prime time offers one of them a chance to reset their season. Analyst Emory Hunt, who has excelled in Jets-related picks, highlights this as one of the trickiest games of the week.

Key Betting Trends

  • Chargers vs Giants: Los Angeles favored by 6.5 with simulations pointing toward a comfortable win.
  • Texans vs Titans: Houston expected to cover a -7 spread against struggling Tennessee.
  • Bears vs Raiders: Chicago tipped to pull off a road upset in Las Vegas.
  • Jaguars vs 49ers: Analysts split, with Jacksonville seen as a live underdog.
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